Broad and defensible legal protections

  •  Significant IP portfolio in the US and internationally

Issued Patents

  • 9,464,122 Methods and compositions comprising tau oligomers
  • 9,506,051 Tau protease compositions and methods of use
  • 10,465,001 Antibody-based reagents that specifically recognize toxic oligomeric forms of tau
  • 10,597,649 Tau protease compositions and methods of use
  • 11,104,710 Methods and compositions comprising tau oligomers

Composition of Matter Patents

  • 11,306,075 Benzofuran, bensothiothene, and indole analogs that inhibit the formation of tau oligomers and their methods of use
  • 11,472,776 Composition of matter - Lead series

Patents Pending - US, EU, Canada, and Japan

  • Novel chemical matter, synthetic route, methods of use
  • Notice of Allowance issued by the U.S. Patent and Trademark Office (12/08/2021)

Trademarks

  • One US trademark has been issued (4,760,737); additional trademark filings are anticipated