Oligomerix is seeking solutions to major unmet medical needs with over 10 years research experience in helping define the role of tau protein in neurodegenerative diseases and discovering and developing novel therapeutics for AlzheimerÃ¢â‚¬â„¢s and related tauopathies.
Role of tau protein in AlzheimerÃ¢â‚¬â„¢s disease:
This video shows how the loss of tau protein function leads to structural changes causing the loss of communication between neurons, a defining characteristic of AlzheimerÃ¢â‚¬â„¢s disease.
Oligomerix has further found that tau acquires toxic functions degrading proteins and disrupting memory formation when it forms small soluble aggregates of tau, tau oligomers.
We are discovering therapeutics that target tau protein loss of function and gain of toxicity